Actigall

Actigall is an epimer of chenodeoxycholic acid. It is a mammalian bile acid found first in the bear and is apparently either a precursor or a product of chenodeoxycholate. Its administration changes the composition of bile and may dissolve gallstones. It is used as a cholagogue and choleretic.

Medicinal name:
  • Ursodiol 300 MG Oral Capsule [Actigall]

Actigall - Pharmacology:

Actigall reduces elevated liver enzyme levels by facilitating bile flow through the liver and protecting liver cells.

Actigall mini report

Actigall NDA
NDA - A product marketed under an approved New Drug Application
Actigall HUMAN PRESCRIPTION DRUG
HUMAN PRESCRIPTION DRUG
Start - Stop data
START DATA:
1987-Dec-31
Start - Stop data
STOP DATA
not occurred

Actigall Interactions

Bile acid sequestering agents such as cholestyramine and colestipol may interfere with the action of Ursodiol by reducing its absorption. Aluminum-based antacids have been shown to adsorb bile acids in vitro and may be expected to interfere with Ursodiol in the same manner as the bile acid sequestering agents. Estrogens, oral contraceptives, and clofibrate (and perhaps other lipid-lowering drugs) increase hepatic cholesterol secretion, and encourage cholesterol gallstone formation and hence may counteract the effectiveness of Ursodiol.

Actigall Contraindications

  1. Ursodiol will not dissolve calcified cholesterol stones, radiopaque stones, or radiolucent bile pigment stones. Hence, patients with such stones are not candidates for Ursodiol therapy.
  2. Patients with compelling reasons for cholecystectomy including unremitting acute cholecystitis, cholangitis, biliary obstruction, gallstone pancreatitis, or biliary-gastrointestinal fistula are not candidates for Ursodiol therapy.
  3. Allergy to bile acids.

Manufacturers name:

  • Watson Pharma, Inc

Generic name, Overdose, Half Life Actigall, Food Interactions, Chemical, etc..

Actigall see also FDA report Saw Palmetto

General health
Brand Names containing Ursodeoxycholic acid