Avastin Indication:

For treatment of metastatic colorectal cancer

Avastin Mechanism Of Action:

Avastin binds VEGF and prevents the interaction of VEGF to its receptors (Flt-1 and KDR) on the surface of endothelial cells. This prevents blood vessel growth.

Avastin Drug Interactions:

Not Available

Avastin Food Interactions:

Not Available

Avastin Generic Name:

Synonyms:

  • Avastin
  • antiVEGF

Drug Type:

Biotech; Approved; Investigational

Absorption:

Not Available

Toxicity (Overdose):

Not Available

Protein Binding:

Not Available

Biotransformation:

Most likely removed by opsonization via the reticuloendothelial system when bound to endothelial cells, or by human antimurine antibody production

Half Life:

Not Available

Dosage Forms of Avastin:

Solution Intravenous

Chemical IUPAC Name:

Humanized anti-VEGF antibody

Organisms Affected:

Humans and other mammals

Avastin to general, pharmacology

General, pharmacology..