BOTOX

Purified botulinum toxin from Clostridium botulinum, purified from culture via dialysis and acid precipitation.

BOTOX - Pharmacology:

BOTOX blocks neuromuscular transmission by binding to acceptor sites on motor or sympathetic nerve terminals, entering the nerve terminals, and inhibiting the release of acetylcholine. This inhibition occurs as the neurotoxin cleaves SNAP-25, a protein integral to the successful docking and release of acetylcholine from vesicles situated within nerve endings.

BOTOX mini report

BOTOX BLA
BLA - A product marketed under an approved Biologic License Application
BOTOX INTRADERMAL; INTRAMUSCULAR
INTRADERMAL; INTRAMUSCULAR
BOTOX INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION
BOTOX HUMAN PRESCRIPTION DRUG
HUMAN PRESCRIPTION DRUG
BOTOX global name
onabotulinumtoxinA
Start - Stop data
START DATA:
1989-Dec-15
Start - Stop data
STOP DATA
not occurred

BOTOX Interactions

Co-administration of BOTOX® and aminoglycosides or other agents interfering with neuromuscular transmission (e.g., curare-like compounds) should only be performed with caution as the effect of the toxin may be potentiated.

The effect of administering different botulinum neurotoxin serotypes at the same time or within several months of each other is unknown. Excessive neuromuscular weakness may be exacerbated by administration of another botulinum toxin prior to the resolution of the effects of a previously administered botulinum toxin.

BOTOX Contraindications

BOTOX® is contraindicated in the presence of infection at the proposed injection site(s) and in individuals with known hypersensitivity to any BOTOX® ingredient in the formulation.

Generic name, Overdose, Half Life BOTOX, Food Interactions, Chemical, etc..

BOTOX see also FDA report

Brand Names containing Botulinum Toxin Type A