Bactroban Nasal

Bactroban Nasal (pseudomonic acid A, or Bactroban or Centany) is an antibiotic originally isolated from Pseudomonas fluorescens. It is used topically, and is primarily effective against Gram-positive bacteria. Bactroban Nasal is bacteriostatic at low concentrations and bactericidal at high concentrations.
Bactroban Nasal has a unique mechanism of action, which is selective binding to bacterial isoleucyl-tRNA synthetase, which halts the incorporation of isoleucine into bacterial proteins. Because this mechanism of action is not shared with any other antibiotic, mupirocin has few problems of antibiotic cross-resistance.

Bactroban Nasal - Pharmacology:

Bactroban Nasal reversibly binds to bacterial isoleucyl-tRNA synthetase, an enzyme which promotes the conversion of isoleucine and tRNA to isoleucyl-tRNA, resulting in the inhibition of bacterial protein and RNA synthesis.

Bactroban Nasal for patients

Patients should be given the following instructions:

  • Apply approximately one-half of the ointment from the single-use tube directly into one nostril and the other half into the other nostril;
  • Avoid contact of the medication with the eyes;
  • Discard the tube after using, do not re-use;
  • Press the sides of the nose together and gently massage after application to spread the ointment throughout the inside of the nostrils; and
  • Discontinue usage of the medication and call your health care practitioner if sensitization or severe local irritation occurs.

Bactroban Nasal Interactions

No information provided.

Bactroban Nasal Contraindications

This drug is contraindicated in individuals with a history of sensitivity reactions to any of its components.

Bactroban Nasal tags categories:

Generic name, Overdose, Half Life Bactroban Nasal, Food Interactions, Chemical, etc..

Bactroban Nasal see also

Brand Names containing Mupirocin