Clopidogrel sulfate

Clopidogrel sulfate, an antiplatelet agent structurally and pharmacologically similar to ticlopidine, is used to reduce atherosclerotic events such as myocardial infarction, stroke, and vascular death in patients who have had a recent stroke, recent MI, or have established peripheral vascular disease.

Medicinal name:
  • Clopidogrel 75 MG Oral Tablet
  • Clopidogrel 300 MG Oral Tablet

Clopidogrel sulfate - Pharmacology:

The active metabolite of clopidogrel prevents binding of adenosine diphosphate (ADP) to its platelet receptor, impairing the ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. It is proposed that the inhibition involves a defect in the mobilization from the storage sites of the platelet granules to the outer membrane. No direct interference occurs with the GPIIb/IIIa receptor. As the glycoprotein GPIIb/IIIa complex is the major receptor for fibrinogen, its impaired activation prevents fibrinogen binding to platelets and inhibits platelet aggregation. By blocking the amplification of platelet activation by released ADP, platelet aggregation induced by agonists other than ADP is also inhibited by the active metabolite of clopidogrel.

Clopidogrel sulfate for patients

Patients should be told that they may bleed more easily and it may take them longer than usual to stop bleeding when they take Plavix or Plavix combined with aspirin, and that they should report any unusual bleeding to their physician. Patients should inform physicians and dentists that they are taking Plavix and/or any other product known to affect bleeding before any surgery is scheduled and before any new drug is taken.

Clopidogrel sulfate Interactions

Aspirin, warfarin, heparin, NSAIDs

Clopidogrel sulfate Contraindications

The use of Plavix is contraindicated in the following conditions:

· Hypersensitivity to the drug substance or any component of the product.
· Active pathological bleeding such as peptic ulcer or intracranial hemorrhage.

Manufacturers name:

  • Unit Dose Services
  • Carilion Materials Management
  • REMEDYREPACK INC
  • Aurobindo Pharma Limited
  • Teva Pharmaceuticals USA Inc
  • Major Pharmaceuticals
  • ScieGen Pharmaceuticals Inc
  • Legacy Pharmaceutical Packaging
  • PD-Rx Pharmaceuticals, Inc
  • Vensun Pharmaceuticals, Inc
  • Golden State Medical Supply, Inc
  • Sun Pharma Global FZE
  • Mylan Pharmaceuticals Inc
  • International Labs, Inc
  • State of Florida DOH Central Pharmacy
  • Apotex Corp
  • American Health Packaging
  • Mylan Institutional Inc
  • Wockhardt Limited
  • Amneal Pharmaceuticals of New York, LLC
  • Cardinal Health
  • Physicians Total Care, Inc
  • DrReddys Laboratories Limited
  • Preferred Pharmaceuticals, Inc
  • St Marys Medical Park Pharmacy
  • Wockhardt USA LLC
  • Clinical Solutions Wholesale
  • NCS HealthCare of KY, Inc dba Vangard Labs
  • Blenheim Pharmacal, Inc
  • Macleods Pharmaceuticals Limited
  • Torrent Pharmaceuticals Limited
  • Accord Healthcare Inc
  • Aidarex Pharmaceuticals LLC
  • ReadyMeds
  • MedVantx, Inc
  • DIRECT RX
  • Bryant Ranch Prepack

Clopidogrel sulfate tags categories:

Generic name, Overdose, Half Life Clopidogrel sulfate, Food Interactions, Chemical, etc..

Clopidogrel sulfate see also

Cardiovascular
Brand Names containing Clopidogrel