This medicine is a type of chemotherapy for treating cancers of the blood
and certain other cancers. This medicine interferes with the way cancer
cells grow. Take your doses on a regular scheduled time and DO NOT take
this medicine more often than directed by your health care provider.
Finish the full course prescribed by your health care provider. DO NOT
stop taking this medicine unless diredted to do so by your health care
provider. While taking this medicine, you make get infection more easily.
Call your doctor if you get a fever, chills, or sore throat. Drink plenty
of water with this medicine.
The rate of metabolism and the leukopenic activity of cyclophosphamide reportedly are increased by chronic administration of high doses of phenobarbital.
The physician should be alert for possible combined drug actions, desirable or undesirable, involving cyclophosphamide even though cyclophosphamide has been used successfully concurrently with other drugs, including other cytotoxic drugs.
Cyclophosphamide treatment, which causes a marked and persistent inhibition of cholinesterase activity, potentiates the effect of succinylcholine chloride.
If a patient has been treated with cyclophosphamide within 10 days of general anesthesia, the anesthesiologist should be alerted.
Continued use of cyclophosphamide is contraindicated in patients with severely depressed bone marrow function. Cyclophosphamide is contraindicated in patients who have demonstrated a previous hypersensitivity to it.