Enbrel Indication:

For treatment of severe adult and juvenille rheumatoid arthritis

Enbrel Mechanism Of Action:

There are two distinct receptors for TNF (TNFRs), a 55 kilodalton protein (p55) and a 75 kilodalton protein (p75). The biological activity of TNF is dependent upon binding to either cell surface receptor (p75 or p55). Enbrel is a dimeric soluble form of the p75 TNF receptor that can bind to two TNF molecules, thereby effectively removing them from circulation.

Enbrel Drug Interactions:

Not Available

Enbrel Food Interactions:

Not Available

Enbrel Generic Name:

Synonyms:

  • CD120b
  • TNF-R2
  • Tumor necrosis factor receptor 2
  • Tumor necrosis factor receptor superfamily member 1B precursor
  • Tumor necrosis factor receptor type II
  • p75
  • p80 TNF-alpha receptor

Drug Type:

Biotech; Approved; Investigational

Absorption:

Not Available

Toxicity (Overdose):

Not Available

Protein Binding:

Not Available

Biotransformation:

Not Available

Half Life:

102 +/- 30 hrs

Dosage Forms of Enbrel:

Solution Subcutaneous

Chemical IUPAC Name:

Human tumor necrosis factor receptor fusion protein

Organisms Affected:

Humans and other mammals

Enbrel to general, pharmacology

General, pharmacology..