Eulexin Indication:

For the management of locally confined Stage B2-C and Stage D2 metastatic carcinoma of the prostate

Eulexin Mechanism Of Action:

Eulexin is a nonsteroidal antiandrogen that blocks the action of both endogenous and exogenous testosterone by binding to the androgen receptor. In addition Eulexin is a potent inhibitor of testosterone-stimulated prostatic DNA synthesis. Moreover, it is capable of inhibiting prostatic nuclear uptake of androgen.

Eulexin Drug Interactions:

Anisindione Eulexin increases the anticoagulant effect
Dicumarol Eulexin increases the anticoagulant effect
Acenocoumarol Eulexin increases the anticoagulant effect
Warfarin Eulexin increases the anticoagulant effect

Eulexin Food Interactions:

Take without regard to meals.

Eulexin Generic Name:

Synonyms:

  • FTA
  • Flutamide USP25

Drug Type:

Small Molecule; Approved

Absorption:

Rapidly and completely absorbed.

Toxicity (Overdose):

In animal studies with flutamide alone, signs of overdose included hypoactivity, piloerection, slow respiration, ataxia, and/or lacrimation, anorexia, tranquilization, emesis, and methemoglobinemia.

Protein Binding:

94-96%

Biotransformation:

Flutamide is rapidly and extensively metabolized, with flutamide comprising only 2.5% of plasma radioactivity 1 hour after administration.

Half Life:

The plasma half-life for the alpha-hydroxylated metabolite of flutamide (an active metabolite) is approximately 6 hours.

Dosage Forms of Eulexin:

Tablet Oral

Chemical IUPAC Name:

2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide

Organisms Affected:

Humans and other mammals

Eulexin to general, pharmacology

General, pharmacology..
Men's Health