Geodon Indication:

For the treatment of schizophrenia

Geodon Mechanism Of Action:

The mechanism of action of Geodon, as with other drugs used to treat schizophrenia, is unknown. Geodon exhibited high in vitro binding affinity for the dopamine D2 and D3, the serotonin 5HT2A, 5HT2C, 5HT1A, 5HT1D and alpha 1-adrenergic receptors, and moderate affinity for the histamine H1 receptor. However, it has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of dopamine Type 2 (D2) and serotonin Type 2 (5HT2) receptor antagonism.

Geodon Drug Interactions:

Not Available

Geodon Food Interactions:

Avoid alcohol.

Geodon Generic Name:

Synonyms:

  • Ziprasidone hydrochloride
  • Ziprasidone mesylate trihydrate

Drug Type:

Small Molecule; Approved

Absorption:

~60%

Toxicity (Overdose):

Not Available

Protein Binding:

99%

Biotransformation:

Hepatic

Half Life:

7 hours

Dosage Forms of Geodon:

Capsule Oral
Powder, for solution Intramuscular

Chemical IUPAC Name:

5-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]-6-chloro-1,3-dihydroindol-2-one

Organisms Affected:

Humans and other mammals

Geodon to general, pharmacology

General, pharmacology..
Depression