Imodium

One of the long-acting synthetic antidiarrheals; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally. .
[PubChem].

Medicinal name:
  • Loperamide Hydrochloride 2 MG Chewable Tablet [Imodium]
  • Loperamide Hydrochloride 2 MG Oral Capsule [Imodium]
  • Loperamide Hydrochloride 2 MG Oral Tablet [Imodium]
  • Loperamide Hydrochloride 2 MG / Simethicone 125 MG Oral Tablet [Imodium Multi-Symptom Relief]

Imodium - Pharmacology:

In vitro and animal studies show that Imodium acts by slowing intestinal motility and by affecting water and electrolyte movement through the bowel. Imodium inhibits peristaltic activity by a direct effect on the circular and longitudinal muscles of the intestinal wall. It is a non-selective calcium channel blocker and binds to opioid mu-receptors. Evidence also suggests that at higher concentrations it binds to NMDA receptors and to calmodulin.

Imodium mini report

Imodium NDA
NDA - A product marketed under an approved New Drug Application
Imodium SOLUTION
SOLUTION
Imodium TABLET
TABLET
Imodium HUMAN OTC DRUG
HUMAN OTC DRUG
Imodium global name
Loperamide Hydrochloride
Imodium global name
loperamide hydrochloride and dimethicone
Start - Stop data
START DATA:
2005-Jan-01
Start - Stop data
STOP DATA
not occurred

Imodium for patients

Patients should be advised to check with their physician if their diarrhea does not improve after a couple of days or if they note blood in their stools or develop a fever.

Imodium Interactions

There was no evidence in clinical trials of drug interactions with concurrent medications.

Imodium Contraindications

Imodium hydrochloride is contraindicated in patients with known hypersensitivity to the drug and in those in whom constipation must be avoided.

Manufacturers name:

  • McNeil Consumer Healthcare Div McNeil-PPC, Inc
  • McNeil Consumer Healthcare
  • Lil Drug Store Products, Inc

Generic name, Overdose, Half Life Imodium, Food Interactions, Chemical, etc..

Imodium see also FDA report

Brand Names containing Loperamide