Take with food, water, or milk to minimize gastric irritation. Swallow the extended-release dosage form whole (do not crush). If you miss a dose, take as soon as possible but do not take if it is almost time for your next dose. DO NOT double up on doses. Notify your doctor if skin tests using allergens is required as this medication may interfere with test results. Avoid use of alcohol or other CNS depressants while taking this medication. This medication can cause drowsiness or dizziness. Use caution while taking this medicine when driving or using equipment. Talk to your doctor if you are taking appetite suppressants. This medication can cause insomnia. Take the medication a few hours before bedtime if this occurs. This medication can cause dryness of mouth - use sugarless gum, candy, ice, or saliva substitute for relief. Check with your dentist if dry mouth continues for more than 2 weeks.
This drug may interact with alcohol or other CNS depressants (may potentiate the CNS depressant effects of either these medications or antihistamines), anticholinergics or other medications with anticholinergic activity (anticholinergic effects may be potentiated when these medications are used concurrently with antihistamines), and monoamine oxidase (MAO) inhibitors (concurrent use with antihistamines may prolong and intensify the anticholinergic and CNS depressant effects of antihistamines).
Contraindicated in the following: blood disease, heart or blood vessel disease (may cause more serious conditions to develop), enlarged prostate, urinary tract blockage or difficult urination (antihistamines may cause urinary problems to become worse), epilepsy (antihistamines may increase the chance of seizures), glaucoma (may cause a slight increase in inner eye pressure that may worsen the condition, jaundice (antihistamines may make the condition worse), liver disease (antihistamines may build up in the body, which may increase the chance of side effects such as muscle spasms), Reyes syndrome (antihistamines may increase the chance of uncontrolled movements).