Motilium - General Information:

A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms. [PubChem]

Drugs categories

Other Brand Names containing Domperidone

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Motilium - Pharmacology:

Gastrointestinal emptying (delayed) adjunct; peristaltic stimulant: The gastroprokinetic properties of domperidone are related to its peripheral dopamine receptor blocking properties. Motilium facilitates gastric emptying and decreases small bowel transit time by increasing esophageal and gastric peristalsis and by lowering esophageal sphincter pressure. Antiemetic: The antiemetic properties of domperidone are related to its dopamine receptor blocking activity at both the chemoreceptor trigger zone and at the gastric level.

Motilium for patients

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Motilium Interactions

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Motilium Contraindications

Domperidone should not be used when patient have gastrointestinal hemorrhage, mechanical obstruction or perforation problems. Domperidone accumulation has been reported in patients with hepatic impairment.

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