Motilium Indication:

For management of dyspepsia, heartburn, epigastric pain, nausea, and vomiting.

Motilium Mechanism Of Action:

Gastrointestinal emptying (delayed) adjunct; peristaltic stimulant: The gastroprokinetic properties of domperidone are related to its peripheral dopamine receptor blocking properties. Motilium facilitates gastric emptying and decreases small bowel transit time by increasing esophageal and gastric peristalsis and by lowering esophageal sphincter pressure. Antiemetic: The antiemetic properties of domperidone are related to its dopamine receptor blocking activity at both the chemoreceptor trigger zone and at the gastric level.

Motilium Drug Interactions:

Not Available

Motilium Food Interactions:

Take 15 to 30 minutes before meals.

Motilium Generic Name:

Synonyms:

  • Not Available

Drug Type:

Small Molecule; Approved

Absorption:

Fast

Toxicity (Overdose):

Side effects include galactorrhea, gynecomastia, or menstrual irregularities.

Protein Binding:

91%-93%

Biotransformation:

Not Available

Half Life:

7 hours

Dosage Forms of Motilium:

Tablet Oral

Chemical IUPAC Name:

6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one

Organisms Affected:

Humans and other mammals

Motilium to general, pharmacology

General, pharmacology..
Gastro Health