Diabetic patient and patient with liver problems or peptic ulcer should take
niacin with caution and should monitor liver funtion test, blood glucose
Niacin should also used with caution in patients with elevated uric acid levels,
gout, unstable angina, and acute phase of myocardial infarction.
Niacin may interact with some antihypertensive drugs, aspirin, and alcohol. Patient should
check with a health professional before start taking niacin or start a new medication.
Interactions for Vitamin B3 (Niacin):
Antihypertensive Therapy: Nicotinic acid may potentiate the effects of ganglionic blocking agents and vasoactive drugs resulting in postural hypotension.
Aspirin: Concomitant aspirin may decrease the metabolic clearance of nicotinic acid. The clinical relevance of this finding is unclear.
Other: Concomitant alcohol or hot drinks may increase the side effects of flushing and pruritus and should be avoided at the time of drug ingestion.
Contraindications for Vitamin B3 (Niacin):
Nicotinic acid is contraindicated in patients with a known hypersensitivity to any component of this medication; significant or unexplained hepatic dysfunction; active peptic ulcer disease; or arterial bleeding.