Noctan - General Information:Noctan is a sedative of the piperidinedione derivative family. This medicine was used for treating insomnia, but is now rarely used as it has been replaced by newer drugs with less side effects, such as benzodiazepines. Noctan was withdrawn from the US market in June 1965 and the Canadian market in September 1990. [Wikipedia]
Other Brand Names containing Methyprylon
Noctan - Pharmacology:
Noctan binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged.
Noctan for patients
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Methyprylon may interact with other addictive medications, in that it may increase the likelyhood of addiction and abuse. Concurrent use of alcohol and other CNS depression-producing drugs may increase the CNS depressant effects of methyprylon or these other medications.
Drug abuse or a history of drug abuse, liver impairment (may increase the half-life of methyprylon), intermittent porphyria can be exacerbated, and sensitivity to methyprylon or any of its ingredients.
Indication, Mechanism Of Action, Drug Interactions, Food Interactions, etc..