Pre-pen

Pre-pen is used as a skin-testing reagent to detect immunoglobulin E antibodies in people with a history of penicillin allergy. The quantitation of in vitro IgE antibodies to the benzylpenicilloyl determinant is a useful tool for evaluating allergic subjects.

Pre-pen - Pharmacology:

The skin test for penicillin demonstrates the presence or absence of specific IgE antibodies to major and minor penicillin determinants. IgE antibodies to major determinants can be detected by using benzylpenicilloyl polylysine. A penicillin skin test predicts only the presence of IgE antibodies for the major or minor penicillin determinants at the time of application and does not predict the future development of IgE-mediated reactions during subsequent courses of penicillin. Benzylpenicilloyl polylysine reacts specifically with penicilloyl skin sensitizing antibodies (reagins) to produce immediate wheal and flare reactions which may reflect increased risk of allergic reactions to subsequent penicillin therapy.

Pre-pen mini report

Pre-pen NDA
NDA - A product marketed under an approved New Drug Application
Pre-pen INTRADERMAL; SUBCUTANEOUS
INTRADERMAL; SUBCUTANEOUS
Pre-pen HUMAN PRESCRIPTION DRUG
HUMAN PRESCRIPTION DRUG
Pre-pen global name
benzylpenicilloyl polylysine
Start - Stop data
START DATA:
1974-Jul-25
Start - Stop data
STOP DATA
not occurred

Pre-pen Interactions

Data is temporarily not available

Pre-pen Contraindications

Skin testing for detection of reagin with specific haptenes is never without risk. Skin testing patients known to be extremely hypersensitive to penicillin should not be done unless there is a very strong medical reason for administering penicillin.

Generic name, Overdose, Half Life Pre-pen, Food Interactions, Chemical, etc..

Pre-pen see also