Quensyl

A chemotherapeutic agent that acts against erythrocytic forms of malarial parasites.

Quensyl - Pharmacology:

Although the exact mechanism of action is unknown, it may be based on ability of hydroxychloroquine to bind to and alter the properties of DNA. Quensyl has also has been found to be taken up into the acidic food vacuoles of the parasite in the erythrocyte. This increases the pH of the acid vesicles, interfering with vesicle functions and possibly inhibiting phospholipid metabolism. In suppressive treatment, hydroxychloroquine inhibits the erythrocytic stage of development of plasmodia. In acute attacks of malaria, it interrupts erythrocytic schizogony of the parasite. Its ability to concentrate in parasitized erythrocytes may account for their selective toxicity against the erythrocytic stages of plasmodial infection. As an antirheumatic, hydroxychloroquine is thought to act as a mild immunosuppressant, inhibiting the production of rheumatoid factor and acute phase reactants. It also accumulates in white blood cells, stabilizing lysosomal membranes and inhibiting the activity of many enzymes, including collagenase and the proteases that cause cartilage breakdown.

Quensyl Interactions

Data is temporarily not available

Quensyl Contraindications

Use of this drug is contraindicated (1) in the presence of retinal or visual field changes attributable to any 4-aminoquinoline compound, (2) in patients with known hypersensitivity to 4-aminoquinoline compounds, and (3) for long-term therapy in children.

Generic name, Overdose, Half Life Quensyl, Food Interactions, Chemical, etc..

Quensyl see also

Antiparasitic
Brand Names containing Hydroxychloroquine