Soxo - General Information:

A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms. [PubChem]

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Soxo - Pharmacology:

Soxo is a competitive inhibitor of the enzyme dihydropteroate synthetase. It inhibits bacterial synthesis of dihydrofolic acid by preventing the condensation of the pteridine with para-aminobenzoic acid (PABA), a substrate of the enzyme dihydropteroate synthetase. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.

Soxo for patients

Sulfisoxazole should be taken with a full glass of water at regular intervals, 1 hour before and 2 hours after a meal. Finish the medication even if you already feel better. To prevent kidney damage, it is important to maintain adequate hydration, 2-3 L/day of fluids.

Sulfisoxazole may cause some side effects, for example:

  • dizziness
  • headache
  • photosensitivity
  • nausea, vomitting, or loss of appetite
  • sore throat, fever, vaginal itching or discharge, unusual bruising or bleeding, fatigue
  • blood in urine or change in urinary pattern
  • swelling of face, lips, or tongue

Talk to you doctor if you plan to become pregnant.

Soxo Interactions

Data is temporarily not available

Soxo Contraindications

Sulfisoxazole should not be given to patients who are hypersensitive to erythromycin, sulfonamides, or any component of the formulation, who have hepatic dysfunction, and porphyria. It is containdicated in infants of less than 2 months of age.

Sulfisoxazole can not be used concurrently with pimozide or cisapride.

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