Stopping this medication suddenly can cause Parkinsons disease to worsen quickly. Report bothersome or unexpected side effects. Unless prescribed, do not take levodopa in addition to this drug. Avoid pyridoxine (vitamin B6) if you are taking levodopa alone, although it can be taken with carbidopa/levodopa. Avoid high-protein meals for maximum absorption. If you are taking the sustained-release tablet, swallow a whole or one-half tablet without chewing or crushing it. Onset of effect of the first morning dose of the sustained release product could be delayed up to 1 hour compared with the quick-release product. A dark color (red, brown, or black) might appear in saliva, urine, or sweat and can stain clothing.
Data is temporarily not available
Monoamine oxidase (MAO) inhibitors and Larodopa should not be given concomitantly and these inhibitors must be discontinued 2 weeks prior to initiating therapy with Larodopa. Larodopa is contraindicated in patients with known hypersensitivity to the drug and in narrow angle glaucoma.
Because levodopa may activate a malignant melanoma, it should not be used in patients with suspicious, undiagnosed skin lesions or a history of melanoma.