An antiviral derivative of thymidine used mainly in the treatment of primary keratoconjunctivitis and recurrent epithelial keratitis due to herpes simplex virus. (From Martindale, The Extra Pharmacopoeia, 30th ed, p557)

TFT - Pharmacology:

TFT interferes with DNA synthesis in cultured mammalian cells. TFT presumably stops replication of herpes viral DNA in 3 ways: 1) competitive inhibition of viral DNA polymerase, 2) incorporation into and termination of the growing viral DNA chain, and 3) inactivation of the viral DNA polymerase. TFT targets HSV and VSV thymidine kinase.

TFT Interactions

No Information Provided.

TFT Contraindications

VIROPTIC Ophthalmic Solution, 1% is contraindicated for patients who develop hypersensitivity reactions or chemical intolerance to trifluridine.

TFT tags categories:

Generic name, Overdose, Half Life TFT, Food Interactions, Chemical, etc..

TFT see also

Brand Names containing Trifluridine