Vermox

A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. .
[PubChem].

Vermox - Pharmacology:

Vermox causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer, and the subsequent release of lysosomes result in decreased production of adenosine triphosphate (ATP), which is the energy required for the survival of the helminth. Due to diminished energy production, the parasite is immobilized and eventually dies.

Vermox for patients

Patients should be informed of the potential risk to the fetus in women taking VERMOX® (mebendazole) during pregnancy, especially during the first trimester .

Patients should also be informed that cleanliness is important to prevent reinfection and transmission of the infection.

Vermox Interactions

Preliminary evidence suggests that cimetidine inhibits mebendazole metabolism and may result in an increase in plasma concentrations of mebendazole.

Vermox Contraindications

VERMOX® (mebendazole) is contraindicated in persons who have shown hypersensitivity to the drug.

Vermox tags categories:

Generic name, Overdose, Half Life Vermox, Food Interactions, Chemical, etc..

Vermox see also Saw Palmetto

Brand Names containing Mebendazole
General health