Zinacef

Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus. .
[PubChem].

Zinacef - Pharmacology:

Zinacef, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefuroxime interferes with an autolysin inhibitor.

Zinacef mini report

Zinacef NDA
NDA - A product marketed under an approved New Drug Application
Zinacef INTRAMUSCULAR; INTRAVENOUS
INTRAMUSCULAR; INTRAVENOUS
Zinacef INTRAVENOUS
INTRAVENOUS
Zinacef INJECTION, POWDER, FOR SOLUTION
INJECTION, POWDER, FOR SOLUTION
Zinacef INJECTION, SOLUTION
INJECTION, SOLUTION
Zinacef HUMAN PRESCRIPTION DRUG
HUMAN PRESCRIPTION DRUG
Start - Stop data
START DATA:
2013-Jan-15
Start - Stop data
STOP DATA
not occurred

Zinacef for patients

Patients should be counseled that antibacterial drugs including Zinacef for Injection USP and Dextrose Injection USP should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). When Zinacef for Injection USP and Dextrose Injection USP is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Zinacef for Injection USP and Dextrose Injection USP or other antibacterial drugs in the future.

Zinacef Interactions

Drug/Laboratory Test Interactions: A false-positive reaction for glucose in the urine may occur with copper reduction tests (Benedictís or Fehlingís solution or with ClinitestÒ tablets) but not with enzyme-based tests for glycosuria. As a false-negative result may occur in the ferricyanide test, it is recommended that either the glucose oxidase or hexokinase method be used to determine blood plasma glucose levels in patients receiving cefuroxime.

Zinacef does not interfere with the assay of serum and urine creatinine by the alkaline picrate method.

Zinacef Contraindications

Zinacef for Injection USP and Dextrose Injection USP is contraindicated in patients with known allergy to the cephalosporin group of antibiotics. Solutions containing dextrose may be contraindicated in patients with hypersensitivity to corn products.

Zinacef tags categories:

Generic name, Overdose, Half Life Zinacef, Food Interactions, Chemical, etc..

Zinacef see also FDA report Hops

Antibacterial