Canesten

An imidazole derivative with a broad spectrum of antimycotic activity. It inhibits biosynthesis of the sterol ergostol, an important component of fungal cell membranes. Its action leads to increased membrane permeability and apparent disruption of enzyme systems bound to the membrane. .
[PubChem].

Canesten - Pharmacology:

Canesten interacts with yeast 14-α demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the membrane. In this way, clotrimazole inhibits ergosterol synthesis, resulting in increased cellular permeability. Canesten may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms and the uptake of purine, impair triglyceride and/or phospholipid biosynthesis, and inhibit the movement of calcium and potassium ions across the cell membrane by blocking the ion transport pathway known as the Gardos channel.

Canesten mini report

Canesten NDA
NDA - A product marketed under an approved New Drug Application
Canesten HUMAN OTC DRUG
HUMAN OTC DRUG
Start - Stop data
START DATA:
2016-May-17
Start - Stop data
STOP DATA
not occurred

Canesten for patients

How to use Canesten :Use clotrimazole exactly as directed by your doctor. Always
read the manufacturers information leaflet, if possible, before beginning treatment.
Canesten preparations are usually applied two to three times a day until the
infection has cleared. This medicine is for you. Never give it to others, even if
their condition appears to be the same as yours. Getting the most from your
treatment : Always wash and dry your hands thoroughly before and after handling
clotrimazole. Do not allow clotrimazole to come into contact with the eyes, ears,
or mucous membranes (eg. mouth, vagina, inside of nose etc.), unless you are advised
to do so by your doctor. Complete the full course of treatment with clotrimazole,
otherwise your infection is likely to recur. Before using any over-the-counter
medicines, check with your pharmacist which medicines are safe for you to use alongside
clotrimazole. You should see an improvement in your condition after a few days.
If your condition does not seem to be getting better after seven days, consult your
doctor for advice.

Canesten Interactions

No information provided.

Canesten Contraindications

MycelexÒ Troches are contraindicated in patients who are hypersensitive to any of its components.

Generic name, Overdose, Half Life Canesten, Food Interactions, Chemical, etc..

Canesten see also Catuaba

Womens Sexual Health

Chemical structure:
N Cl H N H H H H H H H H H H H H H H H H C22H17ClN2 2D chemical structure C22H17ClN2 SVG | 2D structure Clotrimazole chemical names, chemical properties, classification C22H17ClN2