DBI

A biguanide hypoglycemic agent with actions and uses similar to those of metformin. Although it is generally considered to be associated with an unacceptably high incidence of lactic acidosis, often fatal, it is still available in some countries. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)

DBI - Pharmacology:

DBI binds to the AMP-activated protein kinase (AMPK). AMPK is an ultra-sensitive cellular energy sensor that monitors energy consumption and down-regulates ATP-consuming processes when activated. The biguanide phenformin has been shown to independently decrease ion transport processes, influence cellular metabolism and activate AMPK. DBI's hypoglycemic activity is related the effect it has in activating AMPK and fooling insulin sensitive cells into thinking that insulin levels are low and causing the body to use glucose as if in a state of low caloric consumption.

Generic name, Overdose, Half Life DBI, Food Interactions, Chemical, etc..

DBI see also

Brand Names containing Phenformin

Chemical structure:
N N N N N H H H H H H H H H H H H H H H C10H15N5 2D chemical structure C10H15N5 SVG | 2D structure Phenformin chemical names, chemical properties, classification C10H15N5