Femcare Indication:

For the local treatment of oropharyngeal candidiasis and vaginal yeast infections, also used in fungal infections of the skin such as ringworm, athlete's foot, and jock itch.

Femcare Mechanism Of Action:

Femcare interacts with yeast 14-α demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the membrane. In this way, clotrimazole inhibits ergosterol synthesis, resulting in increased cellular permeability. Femcare may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms and the uptake of purine, impair triglyceride and/or phospholipid biosynthesis, and inhibit the movement of calcium and potassium ions across the cell membrane by blocking the ion transport pathway known as the Gardos channel.

Femcare Drug Interactions:

Not Available

Femcare Food Interactions:

Not Available

Femcare Generic Name:


  • Clotrimazol
  • Chlotrimazole

Drug Type:

Small Molecule; Approved


Poorly and erratically absorbed orally, minimal vaginal or topical absorption.

Toxicity (Overdose):

Symptoms of overdose include erythema, stinging, blistering, peeling, edema, pruritus, urticaria, burning, and general irritation of the skin, and cramps.

Protein Binding:



Hepatic (metabolized to inactive metabolites)

Half Life:

2 hours

Dosage Forms of Femcare:

Cream Topical
Cream Intravaginal

Chemical IUPAC Name:


Organisms Affected:

Yeast and other fungi

Femcare to general, pharmacology

General, pharmacology..
Womens Sexual Health