IAB

A sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. .
[PubChem].

IAB - Pharmacology:

Sulfonylureas such as acetohexamide bind to an ATP-dependent K+ channel on the cell membrane of pancreatic beta cells. This inhibits a tonic, hyperpolarizing outflux of potassium, which causes the electric potential over the membrane to become more positive. This depolarization opens voltage-gated Ca2+ channels. The rise in intracellular calcium leads to increased fusion of insulin granulae with the cell membrane, and therefore increased secretion of (pro)insulin.

IAB Interactions

Data is temporarily not available

IAB Contraindications

Contraindicated in kidney disease, liver disease, and thyroid disease.

Generic name, Overdose, Half Life IAB, Food Interactions, Chemical, etc..

IAB see also

Brand Names containing Acetohexamide

Chemical structure:
N O O N S O O H H H H H H H H H H H H H H H H H H H H C15H20N2O4S 2D chemical structure C15H20N2O4S SVG | 2D structure chemical names, chemical properties, classification C15H20N2O4S