A muscarinic antagonist that crosses the blood-brain barrier and is used in the treatment of drug-induced extrapyramidal disorders and in parkinsonism. .

Kemadrin - Pharmacology:

The mechanism of action is unknown. It is thought that Kemadrin acts by blocking central cholinergic receptors, and thus balancing cholinergic and dopaminergic activity in the basal ganglia. Many of its effects are due to its pharmacologic similarities with atropine.

Kemadrin for patients

Patient Information:

Follow your doctors instructions for taking this medicine. This medicine can be taken with food or a snack,
to minimize stomach upset. As your body becomes used to the medicine, it should be taken on an empty
stomach. Talk to your doctor about the best time of day to take the medicine. For patients taking the
extended-release forms, swallow the tablet whole, do NOT CRUSH or CHEW. You may break the tablet in half
if the whole pill is too large for you to take.

This medicine can cause dizziness or drowsiness. Be cautious when driving or performing other hazardous
activities. This medicine can impair judgment. Do NOT increase your dose of this medicine without first
talking to your doctor, even if you feel that the medicine is not working.

Discuss the risks and benefits of using this medicine during pregnancy. It is unknown whether this medicine
is excreted in breast milk. DO NOT breastfeed while taking this medicine until you have talked to your
doctor or pediatrician.

Kemadrin Interactions

Drug Interactions:

Kemadrin can interact with the follwing drugs:

amantadine or rimantadine, narcotic analgesics, amitriptyline (Elavil, Endep), doxepin (Sinequan), or
clomipramine (Anafranil), quinidine (Quinora, Quinaglute, Quinidex, Cardioquin), some antiarrhythmics,
antihistamines (diphenhydramine, chlorpheniramine, triprolidine, brompheniramine, clemastine, etc),
Atenolol, Cholinergic agents (tacrine and donepezil), Digoxin, Levodopa, phenothiazines, chlorpromazine
(Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), mesoridazine (Serentil), thioridazine
(Mellaril), promazine (Sparine), trifluoperazine, and haloperidol.

Drugs other than listed here may also have interactions with Kemadrin.

Kemadrin Contraindications

Procyclidin should not be given to patients with angle-closure glaucoma.

Generic name, Overdose, Half Life Kemadrin, Food Interactions, Chemical, etc..

Kemadrin see also Saw Palmetto

Brand Names containing Procyclidine
General health

Chemical structure:
N O H H H H H H H H H H H H H H H H H H H H H H H H H H H H H C19H29NO 2D chemical structure C19H29NO SVG | 2D structure Procyclidine | Cycrimine | chemical names, chemical properties, classification C19H29NO