A cyclohexanone derivative used for induction of anesthesia. Its mechanism of action is not well understood, but ketamine can block NMDA receptors (receptors, N-methyl-D-aspartate) and may interact with sigma receptors. .

Ketanest - Pharmacology:

Ketanest has several clinically useful properties, including analgesia and less cardiorespiratory depressant effects than other anaesthetic agents, it also causes some stimulation of the cardiocascular system. Ketanest has been reported to produce general as well as local anaesthesia. It interacts with N-methyl-D-aspartate (NMDA) receptors, opioid receptors, monoaminergic receptors, muscarinic receptors and voltage sensitive Ca ion channels. Unlike other general anaesthetic agents, ketamine does not interact with GABA receptors.

Ketanest for patients

As appropriate, especially in cases where early discharge is possible, the duration of ketamine and other drugs employed during the conduct of anesthesia should be considered. The patients should be cautioned that driving an automobile, operating hazardous machinery or engaging in hazardous activities should not be undertaken for 24 hours or more (depending upon the dosage of ketamine and consideration of other drugs employed) after anesthesia.

Ketanest Interactions

Prolonged recovery time may occur if barbiturates and/or narcotics are used concurrently with ketamine.

Ketanest is clinically compatible with the commonly used general and local anesthetic agents when an adequate respiratory exchange is maintained.

Ketanest Contraindications

Ketanest is contraindicated in those in whom a significant elevation of blood pressure would constitute a serious hazard and in those who have shown hypersensitivity to the drug.

Generic name, Overdose, Half Life Ketanest, Food Interactions, Chemical, etc..

Ketanest see also

Brand Names containing Ketamine

Chemical structure:
Cl O N H H H H H H H H H H H H H H H H C13H16ClNO 2D chemical structure C13H16ClNO SVG | 2D structure Ketamine chemical names, chemical properties, classification C13H16ClNO