An ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease. .

MNE - Pharmacology:

MNE acts by inhibiting the postsynaptic alpha(1)-adrenoceptors on vascular smooth muscle. This inhibits the vasoconstrictor effect of circulating and locally released catecholamines (epinephrine and norepinephrine), resulting in peripheral vasodilation. Therefore the mechanism of MNE is to increase vascular circulation in the brain, thereby enhancing the transmission of nerve signals across the nerve fibres, which secrete acetylcholine as a neural transmitter.

Generic name, Overdose, Half Life MNE, Food Interactions, Chemical, etc..

MNE see also

Brand Names containing Nicergoline

Chemical structure:
Br N N N O O O H H H H H H H H H H H H H H H H H H H H H H H H H H C24H26BrN3O3 2D chemical structure C24H26BrN3O3 SVG | 2D structure chemical names, chemical properties, classification C24H26BrN3O3