Meclozine Indication:

For the prevention and treatment of nausea, vomiting, or dizziness associated with motion sickness.

Meclozine Mechanism Of Action:

Along with its actions as an antagonist at H1-receptors, meclizine also possesses anticholinergic, central nervous system depressant, and local anesthetic effects. Meclozine depresses labyrinth excitability and vestibular stimulation and may affect the medullary chemoreceptor trigger zone.

Meclozine Drug Interactions:

Donepezil Possible antagonism of action
Galantamine Possible antagonism of action
Rivastigmine Possible antagonism of action

Meclozine Food Interactions:

Take with food to reduce irritation. Avoid alcohol.

Meclozine Generic Name:


  • Not Available

Drug Type:

Small Molecule; Approved


Well absorbed

Toxicity (Overdose):

Symptoms of overdose include drowsiness and anticholinergic effects. LD50=mg/kg (orally in rat).

Protein Binding:

Not Available



Half Life:

6 hours

Dosage Forms of Meclozine:

Tablet, chewable Oral

Chemical IUPAC Name:


Organisms Affected:

Humans and other mammals

Meclozine to general, pharmacology

General, pharmacology..