Medrol

A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states. .
[PubChem].

Medicinal name:
  • Methylprednisolone 4 MG Oral Tablet [Medrol]
  • Methylprednisolone 8 MG Oral Tablet [Medrol]
  • Methylprednisolone 16 MG Oral Tablet [Medrol]
  • Methylprednisolone 2 MG Oral Tablet [Medrol]
  • Methylprednisolone 32 MG Oral Tablet [Medrol]
  • Pack [Medrol Dosepak]

Medrol - Pharmacology:

Glucocorticoids such as Medrol can inhibit leukocyte infiltration at the site of inflammation, interfere with mediators of inflammatory response, and suppress humoral immune responses. The antiinflammatory actions of glucocorticoids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes. Medrol reduces inflammatory reaction by limiting the capillary dilatation and permeability of the vascular structures. These compounds restrict the accumulation of polymorphonuclear leukocytes and macrophages and reduce the release of vasoactive kinins. Recent research suggests that corticosteroids may inhibit the release of arachidonic acid from phospholipids, thereby reducing the formation of prostaglandins. Medrol is a glucocorticoid receptor agonist. On binding, the corticoreceptor-ligand complex translocates itself into the cell nucleus, where it binds to many glucocorticoid response elements (GRE) in the promoter region of the target genes. The DNA bound receptor then interacts with basic transcription factors, causing an increase or decrease in expression of specific target genes, including suppression of IL2 (interleukin 2) expression.

Medrol mini report

Medrol NDA
NDA - A product marketed under an approved New Drug Application
Medrol HUMAN PRESCRIPTION DRUG
HUMAN PRESCRIPTION DRUG
Medrol global name
Methylprednisole
Medrol global name
methylprednisolone
Medrol global name
Methylprednisolone
Start - Stop data
START DATA:
1957-Oct-24
Start - Stop data
STOP DATA
not occurred

Medrol for patients

Patients who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chickenpox or measles. Patients should also be advised that if they are exposed, medical advice should be sought without delay.

Medrol Interactions

Data is temporarily not available

Medrol Contraindications

Systemic fungal infections.

Manufacturers name:

  • REMEDYREPACK INC
  • Pharmacia and Upjohn Company
  • A-S Medication Solutions LLC
  • Zoetis Inc
  • Stat Rx USA
  • Pharmacia & Upjohn Company

Generic name, Overdose, Half Life Medrol, Food Interactions, Chemical, etc..

Medrol see also FDA report Shiitake

Anti-inflammatories

Chemical structure:
O H H H O O O O H H H H H H H H H H H H H H H H H H H H H H H H H C21H28O5 2D chemical structure C21H28O5 SVG | 2D structure Prednisolone | Aldosterone | chemical names, chemical properties, classification C21H28O5