Periactin Indication:

For treatment of perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, mild uncomplicated allergic skin manifestations of urticaria and angioedema, amelioration of allergic reactions to blood or plasma, cold urticaria, dermatographism, and as therapy for anaphylactic reactions adjunctive to epinephrine.

Periactin Mechanism Of Action:

Periactin competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding.

Periactin Drug Interactions:

Donepezil Possible antagonism of action
Fluoxetine Possible antagonism of action
Galantamine Possible antagonism of action
Metyrapone This combination renders test invalid
Rivastigmine Possible antagonism of action

Periactin Food Interactions:

Take with food.
Avoid alcohol.

Periactin Generic Name:


  • Not Available

Drug Type:

Small Molecule; Approved


Well absorbed after oral administration.

Toxicity (Overdose):

Not Available

Protein Binding:

96 to 99%


Hepatic (cytochrome P-450 system) and some renal.

Half Life:

Not Available

Dosage Forms of Periactin:

Tablet Oral
Syrup Oral

Chemical IUPAC Name:

Not Available

Organisms Affected:

Humans and other mammals

Periactin to general, pharmacology

General, pharmacology..