SMP

Long-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria. .
[PubChem].

SMP - Pharmacology:

SMP is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), a substrate of the enzyme dihydropteroate synthetase. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.

SMP for patients

Patient Information:

Discuss with your doctor about the risks of taking SMP. Make sure you let the doctor know
if you are pregnant, breast feeding, or you have liver, renal problems or any other medical conditions.

SMP Interactions

Drug Interactions:

SMP increases the effects of the some drugs, including:
ACETOHEXAMIDE
CHLORPROPAMIDE
CLOZAPINE
GLIBENCLAMIDE
GLIBORNURIDE
GLICLAZIDE
GLIMEPIRIDE
GLIPIZIDE
GLIQUIDONE
GLYMIDINE
TOLAZAMIDE
TOLBUTAMIDE

SMP decreases the effects of the follwing drugs:
ETHINYLESTRADIOL
ORAL CONTRACEPTIVES
POTASSIUM AMINOBENZOATE

SMP Contraindications

SMP is contraindicated in patients who are allergic to Sulfonamide, or have adverse
reactions to cotrimoxazole or sulphonamides. It is also contraindicated in the following medical
conditions:
Disorders of porphyrin metabolism
Glucose-6-phosphate dehydrogenase deficiency anaemia
Sulphonamide poisoning

Generic name, Overdose, Half Life SMP, Food Interactions, Chemical, etc..

SMP see also

Brand Names containing Sulfametopyrazine

Chemical structure:
N N N O S O O N H H H H H H H H H H H H C11H12N4O3S 2D chemical structure C11H12N4O3S SVG | 2D structure Sulfametopyrazine chemical names, chemical properties, classification C11H12N4O3S