Salagen

A slowly hydrolyzed muscarinic agonist with no nicotinic effects. Salagen is used as a miotic and in the treatment of glaucoma. .
[PubChem].

Medicinal name:
  • Pilocarpine Hydrochloride 7.5 MG Oral Tablet [Salagen]
  • Pilocarpine Hydrochloride 5 MG Oral Tablet [Salagen]

Salagen - Pharmacology:

Salagen is a cholinergic parasympathomimetic agent. It increase secretion by the exocrine glands, and produces contraction of the iris sphincter muscle and ciliary muscle (when given topically to the eyes) by mainly stimulating muscarinic receptors.

Salagen mini report

Salagen NDA
NDA - A product marketed under an approved New Drug Application
Salagen TABLET, FILM COATED
TABLET, FILM COATED
Salagen HUMAN PRESCRIPTION DRUG
HUMAN PRESCRIPTION DRUG
Salagen global name
pilocarpine hyrochloride
Start - Stop data
START DATA:
1994-Mar-22
Start - Stop data
STOP DATA
not occurred

Salagen for patients

Patients should be informed that pilocarpine may cause visual disturbances, especially at night, that could impair their ability to drive safely.

If a patient sweats excessively while taking pilocarpine hydrochloride and cannot drink enough liquid, the patient should consult a physician. Dehydration may develop.

Salagen Interactions

Salagen should be administered with caution to patients taking beta adrenergic antagonists because of the possibility of conduction disturbances. Drugs with parasympathomimetic effects administered concurrently with pilocarpine would be expected to result in additive pharmacologic effects. Salagen might antagonize the anticholinergic effects of drugs used concomitantly. These effects should be considered when anticholinergic properties may be contributing to the therapeutic effect of concomitant medication (e.g., atropine, inhaled ipratropium).

While no formal drug interaction studies have been performed, the following concomitant drugs were used in at least 10% of patients in either or both Sjögrens efficacy studies: acetylsalicylic acid, artificial tears, calcium, conjugated estrogens, hydroxychloroquine sulfate, ibuprofen, levothyroxine sodium, medroxyprogesterone acetate, methotrexate, multivitamins, naproxen, omeprazole, paracetamol, and prednisone.

Salagen Contraindications

SALAGEN® Tablets are contraindicated in patients with uncontrolled asthma, known hypersensitivity to pilocarpine, and when miosis is undesirable, e.g., in acute iritis and in narrow-angle (angle closure) glaucoma.

Manufacturers name:

  • Eisai Inc

Generic name, Overdose, Half Life Salagen, Food Interactions, Chemical, etc..

Salagen see also FDA report

Brand Names containing Pilocarpine

Chemical structure:
N N O O H H H H H H H H H H H H H H H H C11H16N2O2 2D chemical structure C11H16N2O2 SVG | 2D structure Pilocarpine chemical names, chemical properties, classification C11H16N2O2