The enzyme collagenase is derived from fermentation of Clostridium histolyticum

Santyl - Pharmacology:

Santyl is a protease that is specific to collagen. The triple helical region of interstitial collagens is highly resistant to most cell proteinases. However, during remodeling of the connective tissue in such processes as wound healing and metastasis, collagen becomes susceptible to cleavage by collagenases. Santyl cleaves all 3 alpha helical chains of native Types I, II and III collagens at a single locus by hydrolyzing the peptide bond following the Gly residue of the sequence: Gly 775-(Ile or Leu) 776-(Ala or Leu) 777 located approximately three-fourths of the chain length from each N-terminus

Santyl Interactions

Data is temporarily not available

Santyl Contraindications

Santyl Santyl® Ointment is contraindicated in patients who have shown local or systemic hypersensitivity to collagenase.

Generic name, Overdose, Half Life Santyl, Food Interactions, Chemical, etc..

Santyl see also