An anticonvulsant effective in absence seizures, but generally reserved for refractory cases because of its toxicity. (From AMA Drug Evaluations Annual, 1994, p378)

Tridone - Pharmacology:

Dione anticonvulsants reduce T-type calcium currents in thalamic neurons, including thalamic relay neurons. This raises the threshold for repetitive activity in the thalamus, and inhibits corticothalamic transmission. Thus, the abnormal thalamocortical rhythmicity, which is thought to underlie the 3-Hz spike-and-wave discharge seen on electroencephalogram(EEG) with absence seizures, is dampened.

Tridone Interactions

Data is temporarily not available

Tridone Contraindications

Contraindicated in liver disease, kidney disease, retinal or optic nerve (eye) disease, a disease of the blood or bone marrow, and acute intermittent porphyria.

Generic name, Overdose, Half Life Tridone, Food Interactions, Chemical, etc..

Tridone see also

Brand Names containing Trimethadione

Chemical structure:
O O O N H H H H H H H H H C6H9NO3 2D chemical structure C6H9NO3 SVG | 2D structure Trimethadione chemical names, chemical properties, classification C6H9NO3