An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels. .

Vasal - Pharmacology:

Perhaps by its direct vasodilating action on cerebral blood vessels, Vasal increases cerebral blood flow and decreases cerebral vascular resistance in normal subjects; oxygen consumption is unaltered. These effects may explain the benefit reported from the drug in cerebral vascular encephalopathy.

Vasal Interactions

No information provided.


Vasal Contraindications

Intravenous injection of papaverine is contraindicated in the presence of complete atrioventricular heart block. When conduction is depressed, the drug may produce transient ectopic rhythms of ventricular origin, either premature beats or paroxysmal tachycardia.

Vasal hydrochloride is not indicated for the treatment of impotence by intracorporeal injection. The intracorporeal injection of papaverine hydrochloride has been reported to have resulted in persistent priapism requiring medical and surgical intervention.

Generic name, Overdose, Half Life Vasal, Food Interactions, Chemical, etc..

Vasal see also

Brand Names containing Papaverine

Chemical structure:
N O O O O H H H H H H H H H H H H H H H H H H H H H C20H21NO4 2D chemical structure C20H21NO4 SVG | 2D structure Papaverine chemical names, chemical properties, classification C20H21NO4