VELCADE® (bortezomib) for Injection
VELCADE is intended for use under the guidance and supervision of a healthcare professional. Please discuss the
possibility of the following side effects with your doctor:
Effects on Ability to Drive or Operate Machinery or Impairment of Mental Ability: VELCADE may cause
low blood pressure that may lead to tiredness, dizziness, fainting, or blurred vision. Do not drive any vehicle or
operate any dangerous tools or machinery if you experience these side effects. Even if you have not felt these
effects previously, you must still be cautious.
Pregnancy/Nursing: Please use effective contraceptive measures to prevent pregnancy during treatment
with VELCADE. It is advised that you are not given VELCADE if you are pregnant. You must make sure that you do not
become pregnant while receiving VELCADE, but if you do, inform your doctor immediately. It is advised that you do not
breast feed while you are receiving VELCADE. If you wish to restart breast feeding after your VELCADE treatment, you
must discuss this with your doctor or nurse, who will tell you when it is safe to do so.
Dehydration/Hypotension: Following the use of VELCADE therapy, you may experience vomiting and/or
diarrhea. Drink plenty of fluids. Speak with your doctor if these symptoms occur about what you should do to control
or manage these symptoms. If you experience symptoms of dizziness or light-headedness, consult a healthcare
professional. Seek immediate medical attention if you experience fainting spells.
Concomitant Medications: Please speak with your doctor about any other medication you are currently
taking. Your doctor will want to be aware of any other medications.
Diabetic Patients: If you are a patient on oral antidiabetic medication while receiving VELCADE
treatment, please check your blood sugar level frequently. Please call your doctor if you notice an unusual
Peripheral Neuropathy: Contact your doctor if you experience new or worsening symptoms of peripheral
neuropathy such as tingling, numbness, pain, or a burning feeling in the feet or hands.
Congestive Heart Failure: Contact your doctor if you experience shortness of breath or swelling of
the feet, ankles, or legs.