Zerit Indication:

For the treatment of human immunovirus (HIV) infections.

Zerit Mechanism Of Action:

Zerit inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP and by its incorporation into viral DNA.

Zerit Drug Interactions:

Not Available

Zerit Food Interactions:

Not Available

Zerit Generic Name:


  • STV
  • Estavudina [Inn-Spanish]
  • Sanilvudine
  • Stavudine [Usan:Ban:Inn]
  • Stavudinum [Inn-Latin]
  • 2',3'-Didehydro-3'-deoxythimidine
  • 3'-Deoxy-2'-thymidinene

Drug Type:

Small Molecule; Approved


Following oral administration, stavudine is rapidly absorbed (bioavailability is 68-104%).

Toxicity (Overdose):

Side effects include peripheral neuropathy tingling, burning, numbness, or pain in the hands or feet), fatal lactic acidosis has been reported in patients treated with stavudine (ZERIT) in combination with other antiretroviral agents, severe liver enlargement, inflammation (pain and swelling) of the liver, and liver failure.

Protein Binding:



Phosphorylated intracellularly to stavudine triphosphate, the active substrate for HIV-reverse transcriptase.

Half Life:

0.8-1.5 hours (in adults)

Dosage Forms of Zerit:

Capsule Oral

Chemical IUPAC Name:


Organisms Affected:

Human Immunodeficiency Virus

Zerit to general, pharmacology

General, pharmacology..
Anti Viral