Zetia Indication:

For use as adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, and Apo B in patients with primary (heterozygous familial and non-familial) hypercholesterolemia.

Zetia Mechanism Of Action:

Zetia localizes and appears to act at the brush border of the small intestine and inhibits the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver.

Zetia Drug Interactions:

Cholestyramine Cholestyramine decreases the levels of ezetimibe
Cyclosporine Cyclosporine increases the effect and toxicity of ezetimibe

Zetia Food Interactions:

Take without regard to meals.

Zetia Generic Name:


  • Not Available

Drug Type:

Small Molecule; Approved


Not Available

Toxicity (Overdose):

Not Available

Protein Binding:



Hepatic, intestinal wall

Half Life:

22 hours

Dosage Forms of Zetia:

Tablet Oral

Chemical IUPAC Name:


Organisms Affected:

Humans and other mammals

Zetia to general, pharmacology

General, pharmacology..