Zinat Indication:

For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.

Zinat Mechanism Of Action:

Zinat, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefuroxime interferes with an autolysin inhibitor.

Zinat Drug Interactions:

Probenecid Probenecid increases the antibiotic's level

Zinat Food Interactions:

Take with food to increase absorption.

Zinat Generic Name:

Synonyms:

  • Cefuroxime [USAN:BAN:INN]
  • Cefuroximo [INN-Spanish]
  • Cefuroximum [INN-Latin]
  • Cefuroxim

Drug Type:

Small Molecule; Approved

Absorption:

Absorbed from the gastrointestinal tract. Absorption is greater when taken after food (absolute bioavailability increases from 37% to 52%).

Toxicity (Overdose):

Allergic reactions might be expected, including rash, nasal congestion, cough, dry throat, eye irritation, or anaphylactic shock. Overdosage of cephalosporins can cause cerebral irritation leading to convulsions.

Protein Binding:

50% to serum protein

Biotransformation:

The axetil moiety is metabolized to acetaldehyde and acetic acid.

Half Life:

Approximately 80 minutes following intramuscular or intravenous injection.

Dosage Forms of Zinat:

Powder, for solution Oral
Tablet Oral
Powder, for solution Intravenous

Chemical IUPAC Name:

(6R,7R)-3-(carbamoyloxymethyl)-7-[[(2E)-2-furan-2-yl-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Organisms Affected:

Enteric bacteria and other eubacteria

Zinat to general, pharmacology

General, pharmacology..